YK-11 Key Points
- Steroidal SARM
- No Human or Animal Studies
- Efficacy and Safety Unknown
YK-11 History
YK11 was first described in 2011 by Kanno et al. It has appeared in a couple of cell incubation studies, where it demonstrated selective SARM-like effects. It is unclear if this drug is on track for development as a medicine at this time. YK11 is on the WADA banned substance list, and is detectable in doping controls.
Structural Characteristics of YK-11
YK11 is a synthetic steroidal ligand for the androgen receptor (SARM). It has the chemical name (17a ,20E)-17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic Acid Methyl Ester. Its serum half-life is unknown.
How is YK-11 Supplied
YK11 is not available as a pharmaceutical product. Standard dosage information is currently unavailable. Gray market preparations commonly contain 4-5 mg per capsule, or varying concentrations in oral solution.
YK-11 Warnings/Side Effects
YK11 is an unapproved new drug. A thorough understanding of its safety and propensity for side effects in humans is lacking at this time. This drug is steroidal in structure and activity. As such, it is likely to have some side effects in common with other anabolic steroids. Use of YK11 has never been studied in humans, however. It is unknown what shared or unique side effects it may actually have, or if there is any unusual toxicity.
YK-11 Administration
YK11 is given orally. This substance has not been approved for use in humans. Prescribing guidelines are unavailable.
When used for physique- or performance-enhancing purposes, YK 11 is commonly used at a dosage of 5-10 mg per day (men). Women usually opt for 1-5 mg daily, as its propensity for virilizing side effects is unknown.The total daily dose is usually given in one application, though some do opt to split this into two episodes given uncertainties about half-life.
Cycles of YK11 usually last 4 to 8 weeks. Anecdotal reports do suggest this drug has a distinct anabolic effect, and it is often regarded as being among the more potent drugs in the SARM class for gaining lean mass and strength. Beyond that, we are not in a position to categorize its effects.
YK-11 Availability
YK11 is not available as a prescription drug product. It is sold exclusively as a "research compound" or gray market supplement. Note that the quality of gray market products can be difficult to assure.
References
Wlliam Llewellyn (2017) - Anabolics