Testosterone Enanthate History
Testosterone enanthate first appeared on Western drug markets during the early 1950’s. It was the first slow-acting oil-based injectable ester of testosterone to be widely adopted in Western medicine, and effectively replaced testosterone propionate and testosterone suspension for most therapeutic uses. The first brand of this drug to be sold in the U.S. was Delatestryl by Squibb. Over the years the Delatestryl brand has changed hands several times, most notably to Mead Johnson, BTG, Savient, and in December 2005, Indevus. The most prominent brand of testosterone enanthate outside of the United States is Testoviron, a drug that has seen uninterrupted production by the same manufacturer (Schering AG, Germany) for more than 50 years. Globally, the Testoviron brand from Schering is the single most widely used injectable testosterone preparation.
Testosterone enanthate is most often used clinically to replace normal levels of testosterone in adult males suffering diminished androgen levels. This may manifest itself with a loss of libido, lean muscle mass, and normal energy and vigor. Testosterone enanthate is also used to treat undescended testicles and delayed puberty in adolescent males, and occasionally as a secondary medication during inoperable breast cancer in women. This form of testosterone has also been studied with great success as a male birth control option. Weekly injections of 200 mg were shown to efficiently lower sperm production for most men within three months of treatment, a state of suppression that remained until after the drug was discontinued. With the current stigma surrounding anabolic/androgenic steroids, however, it is unlikely that such therapy will become adopted in Western medical practice. Today, in spite of the growing number of alternative therapies, testosterone enanthate remains the most widely prescribed form of testosterone in the world.
How is Testosterone Enanthate Supplied
Testosterone enanthate is widely available in human and veterinary drug markets. Composition and dosage may vary by country and manufacturer, but usually contain 50 mg/ml, 100 mg/ml, 200 mg/ml, or 250 mg/ml of steroid dissolved in oil.
Structural Characteristics of Testosterone Enanthate
Testosterone enanthate is a modified form of testosterone, where a carboxylic acid ester (enanthoic acid) has been attached to the 17-beta hydroxyl group. Esterified forms of testosterone are less polar than free testosterone, and are absorbed more slowly from the area of injection. Once in the bloodstream, the ester is removed to yield free (active) testosterone. Esterified forms of testosterone are designed to prolong the window of therapeutic effect following administration, allowing for a less frequent injection schedule compared to injections of free (unesterified) steroid. The half-life of testosterone enanthate is approximately eight days after injection.
Testosterone Enanthate Side Effects (Estrogenic)
Testosterone is readily aromatized in the body to estradiol (estrogen). The aromatase (estrogen synthetase) enzyme is responsible for this metabolism of testosterone. Elevated estrogen levels can cause side effects such as increased water retention, body fat gain, and gynecomastia. Testosterone is considered a moderately estrogenic steroid. An anti-estrogen such as clomiphene citrate or tamoxifen citrate may be necessary to prevent estrogenic side effects. One may alternately use an aromatase inhibitor like Arimidex (anastrozole), which more efficiently controls estrogen by preventing its synthesis. Aromatase inhibitors can be quite expensive in comparison to anti-estrogens, however, and may also have negative effects on blood lipids.
Estrogenic side effects will occur in a dose-dependant manner, with higher doses (above normal therapeutic levels) of testosterone more likely to require the concurrent use of an antiestrogen or aromatase inhibitor. Since water retention and loss of muscle definition are common with higher doses of testosterone, this drug is usually considered a poor choice for dieting or cutting phases of training. Its moderate estrogenicity makes it more ideal for bulking phases, where the added water retention will support raw strength and muscle size, and help foster a stronger anabolic environment.
Testosterone Enanthate Side Effects (Androgenic)
Testosterone is the primary male androgen, responsible for maintaining secondary male sexual characteristics. Elevated levels of testosterone are likely to produce androgenic side effects including oily skin, acne, and body/facial hair growth. Men with a genetic predisposition for hair loss (androgenetic alopecia) may notice accelerated male pattern balding. Those concerned about hair loss may find a more comfortable option in nandrolone decanoate, which is a comparably less androgenic steroid. Women are warned of the potential virilizing effects of anabolic/androgenic steroids, especially with a strong androgen such as testosterone. These may include deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.
In androgen-responsive target tissues such as the skin, scalp, and prostate, the high relative androgenicity of testosterone is dependant on its reduction to dihydrotestosterone (DHT). The 5-alpha reductase enzyme is responsible for this metabolism of testosterone. The concurrent use of a 5-alpha reductase inhibitor such as finasteride or dutasteride will interfere with site-specific potentiation of testosterone action, lowering the tendency of testosterone drugs to produce androgenic side effects. It is important to remember that anabolic and androgenic effects are both mediated via the cytosolic androgen receptor. Complete separation of testosterone’s anabolic and androgenic properties is not possible, even with total 5-alpha reductase inhibition.
Testosterone Enanthate Side Effects (Hepatotoxicity)
Testosterone does not have hepatotoxic effects; liver toxicity is unlikely. One study examined the potential for hepatotoxicity with high doses of testosterone by administering 400 mg of the hormone per day (2,800 mg per week) to a group of male subjects. The steroid was taken orally so that higher peak concentrations would be reached in hepatic tissues compared to intramuscular injections. The hormone was given daily for 20 days, and produced no significant changes in liver enzyme values including serum albumin, bilirubin, alanine-amino-transferase, and alkaline phosphatases.
Testosterone Enanthate Side Effects (Cardiovascular)
Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to reduce HDL (good) cholesterol values and increase LDL (bad) cholesterol values, which may shift the HDL to LDL balance in a direction that favors greater risk of arteriosclerosis. The relative impact of an anabolic/androgenic steroid on serum lipids is dependant on the dose, route of administration (oral vs. injectable), type of steroid (aromatizable or non-aromatizable), and level of resistance to hepatic metabolism. Anabolic/androgenic steroids may also adversely effect blood pressure and triglycerides, reduce endothelial relaxation, and support left ventricular hypertrophy, all potentially increasing the risk of cardiovascular disease and myocardial infarction.
Testosterone tends to have a much less dramatic impact on cardiovascular risk factors than synthetic steroids. This is due in part to its openness to metabolism by the liver, which allows it to have less effect on the hepatic management of cholesterol. The aromatization of testosterone to estradiol also helps to mitigate the negative effects of androgens on serum lipids. In one study, 280 mg per week of testosterone ester (enanthate) had a slight but not statistically significant effect on HDL cholesterol after 12 weeks, but when taken with an aromatase inhibitor a strong (25%) decrease was seen. Studies using 300 mg of testosterone ester (enanthate) per week for 20 weeks without an aromatase inhibitor demonstrated only a 13% decrease in HDL cholesterol, while at 600 mg the reduction reached 21%. The negative impact of aromatase inhibition should be taken into consideration before such drug is added to testosterone therapy.
Due to the positive influence of estrogen on serum lipids, tamoxifen citrate or clomiphene citrate are preferred to aromatase inhibitors for those concerned with cardiovascular health, as they offer a partial estrogenic effect in the liver. This allows them to potentially improve lipid profiles and offset some of the negative effects of androgens. With doses of 600 mg or less per week, the impact on lipid profile tends to be noticeable but not dramatic, making an anti-estrogen (for cardioprotective purposes) perhaps unnecessary. Doses of 600 mg or less per week have also failed to produce statistically significant changes in LDL/VLDL cholesterol, triglycerides, apolipoprotein B/C-III, C-reactive protein, and insulin sensitivity, all indicating a relatively weak impact on cardiovascular risk factors. When used in moderate doses, injectable testosterone esters are usually considered to be the safest of all anabolic/androgenic steroids.
To help reduce cardiovascular strain it is advised to maintain an active cardiovascular exercise program and minimize the intake of saturated fats, cholesterol, and simple carbohydrates at all times during active AAS administration. Supplementing with fish oils (4 grams per day) and a natural cholesterol/antioxidant formula such as Lipid Stabil or a product with comparable ingredients is also recommended.
Testosterone Enanthate Side Effects (Testosterone Suppression)
All anabolic/androgenic steroids when taken in doses sufficient to promote muscle gain are expected to suppress endogenous testosterone production. Testosterone is the primary male androgen, and offers strong negative feedback on endogenous testosterone production. Testosterone-based drugs will, likewise, have a strong effect on the hypothalamic regulation of natural steroid hormones. Without the intervention of testosterone-stimulating substances, testosterone levels should return to normal within 1-4 months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse, necessitating medical intervention.
As with all anabolic/androgenic steroids, it is unlikely that one will retain every pound of new bodyweight after a cycle is concluded. This is especially true when withdrawing from a strong (aromatizing) androgen like testosterone, as much of the new weight gain is likely to be in the form of water retention; quickly eliminated after drug discontinuance. An imbalance of anabolic and catabolic hormones during the post-cycle recovery period may further create an environment that is unfavorable for the retention of muscle tissue. Proper ancillary drug therapy is usually recommended to help restore hormonal balance more quickly, ultimately helping the user retain more muscle tissue.
Testosterone Enanthate Administration (Men)
To treat androgen insufficiency, the prescribing guidelines for testosterone enanthate call for a dosage of 50-400 mg every 2 to 4 weeks. Although active in the body for a longer time, testosterone enanthate is usually injected on a weekly basis for muscle-building purposes. The usual dosage for physique- or performance-enhancing purposes is in the range of 200- 600 mg per week, taken in cycles 6 to 12 weeks in length. This level is sufficient for most users to notice exceptional gains in muscle size and strength.
Testosterone is usually incorporated into bulking phases of training, when added water retention will be of little consequence, the user more concerned with raw mass than definition. Some do incorporate the drug into cutting cycles as well, but typically in lower doses (100- 200 mg per week) and/or when accompanied by an aromatase inhibitor to keep estrogen levels under control. Testosterone enanthate is a very effective anabolic drug, and is often used alone with great benefit. Some, however, find a need to stack it with other anabolic/androgenic steroids for a stronger effect, in which case an additional 200-400 mg per week of boldenone undecylenate, methenolone enanthate, or nandrolone decanoate should provide substantial results with no significant hepatotoxicity. Testosterone is ultimately very versatile, and can be combined with many other anabolic/androgenic steroids to tailor the desired effect.
Testosterone Enanthate Administration (Women)
Testosterone enanthate is rarely used with women in clinical medicine. When applied, it is most often used as a secondary medication during inoperable breast cancer, when other therapies have failed to produce a desirable effect and suppression of ovarian function is necessary. Testosterone enanthate is not recommended for women for physique- or performance-enhancing purposes due to its strong androgenic nature, tendency to produce virilizing side effects, and slow-acting characteristics (making blood levels difficult to control).
Testosterone Enanthate Availability
Testosterone enanthate remains the most widely manufactured form of injectable testosterone worldwide. It is produced in many generic and brand name forms. In reviewing some of the products and changes in the global pharmaceutical market, we have made the following observations.
In 2006, Savient sold the rights for Delatestryl to Indevus (United States). Indevus subsequently became a subsidiary of Endo Pharmaceuticals in March of 2009. Brand name Delatestryl remains available in the United States under the new company (at 200 mg/mL strength).
Generic versions are also available in the United States (also at a dosage of 200 mg/mL) by Watson, Paddock, and Synerex.
Norma Hellas (Greece), makers of Norma Hellas Nandrolone, recently added a generic 250 mg/mL testosterone enanthate injectable to their product offerings. It comes in a single dark amber 1 mL glass ampule,and is packaged 1 ampule per box. Be sure to look at the Greek Pharmacy sticker under UV light to assure you have a legitimate product.
Bayer took control of Schering AG in December 2006. Following this acquisition, the Schering Primoteston and Testoviron Depot products were transitioned over to the Bayer brand and logo (the products now bear the full company name Bayer Schering Pharma). Note that many counterfeiters have not yet made this change in their own products, and thus are still duplicating the old Schering labels and boxes.
Cidoteston is produced in Egypt by CID (Chemical Industries Development). It comes in 1 mL ampules, containing 250 mg/mL of steroid. This product has been counterfeited, though the current most popular copy can be quickly identified by close examination of the fine details (logo, graphics) on the box.
The French version Testosterone Heptylate is still in production. It is now sold under the S.E.R.P. label, and available in the familiar 250 mg/mL strength and 1 mL ampule. This drug is frequently exported to developing markets with close trade relations to France, such as Lebanon.
Androtardyl is also produced in France, and occasionally circulates on the black market. Again, be sure to look for the proper box before buying.
Testo-Enant is another brand in Europe, this one being made by Geymonat in Italy. These ampules contain 250 mg of steroid, either in 1 mL or 2 mL of oil. Currently fakes are not a problem; however, this steroid is not found on the black market in high volumes.
Galenika makes Testosteron Depo in Serbia. These 1 mL ampules contain 250 mg/mL of steroid, and are extremely cheap at the retail level in their country of origin.
Jelfa produces Testosteronum Prolongatum in Poland. It is made at a dosage of 100 mg/mL. Each box contains five 1 mL ampules, which are themselves made of clear glass and carry a paper label.The packaging of this product was recently updated to reflect a more modern color-gradient design.
Testoviron Depot from German Remedies in India remains in production. The product comes is made in foil and plastic blister packs.
The Indian export firm Alpha-Pharma also makes a testosterone enanthate, called Testobolin. It comes in 1 mL glass ampules.
Testofort Inj from Albert Davis Pakistan is commonly found on the international market. It contains 250 mg/ml of steroid in 1 mL ampules. Three ampules come packaged to each cardboard box.
Geofman Pharmaceuticals also makes a generic in Pakistan.The product contains 250 mg of steroid in each 1 mL ampule. Like Testofort, three ampules are contained in each box. Note that the lot number and expiration date are electronically printed on the bottom inside flap of the box, in addition to the proper placement on the outside.
Aburaihan makes a generic enanthate in Iran, which is becoming increasingly popular on the black market. Note that the packaging of this product was recently updated. Counterfeits of black market. Note that the packaging of this product was recently updated. Counterfeits of this product have historically been a problem.
Balkan Pharmaceuticals (Moldova) makes the product Testosterona E. It is prepared in both 1 mL ampules and multi-dose vials.
Testosterone Enanthate is produced by Swiss Remedies and available across Europe. Due to numerous fakes of this product, Swiss Remedies offers a convenient online product checker.
Magnus Pharmaceuticals makes the product Test E primarily for the EU and UK markets. Due to fake products appearing on the market, Magnus offers an online checker that lets steroid users verify their product originality.
Testosterone was generally toted as the big daddy of injectable steroids. No other steroid was consistently reported to bring such high returns as quickly in weight gain and strength increases. Due to its high anabolic/high androgenic effects, many athletes used this drug in an off-season mass cycle. Water retention during administration of ENANTHATE was not reportedly as high as that realized during the use of OMNADREN… but darn close. Like all testosterone esters, Enanthate aromatized easily and has a high conversion rate to DHT. Those with prostate problems or who were sensitive to gyno and female pattern fat deposits, readily agreed that they should have either left it alone or taken steps to suppress estrogenic activity due to aromatization. Drugs such as PROVIRON and NOVLADEX were often utilized for this reason.
DHT conversion enzyme blockers such as Proscar were commonly co-administered with testosterones for the former reason. Testosterone enanthate notably suppressed HPTA function severely. HCG/Clomid were considered almost a must to stimulate normal endogenous (natural) testosterone production within a positive period of time at post use. My personal experience has been that if a cycle containing testosterone enanthate lasted longer than 6 weeks, HCG and usually Clomid were introduced for 10 days beginning at the end of week #4. (5000 i.u. of HCG 3 times in 10 days usually normalized sperm and endogenous testosterone production to a respectable extent) Without the use of HPTA stimulating compounds normalization did occur, only at a much slower rate. For this reason, gains made during "enanthate only" administrations were not well maintained after use was discontinued, and much was lost needlessly by most regardless. Perhaps this was why so many uninformed individuals stayed on the stuff almost year round. (There are several solutions and protocols that prevented excessive post-cycle lean mass tissue loss for the more informed athletes).
Males injected 200-1000mg weekly. Some did use much higher dosages of course. Due to a plasma half-life of 4-5 days, injections were normally administered biweekly. Most novice steroid should not use testosterone. Not only was considered unnecessary, it would have been foolish to diminish possible later gains when more gentle AAS were no longer providing results at reasonable dosages. Most users made excellent progress with a total weekly dosage of 200-600mg. Post-cycle use of an anticatabolic drug was a constant agreed upon factor since it helped to maintain gains. (See Clenbuterol).
The negative side effects reported were mostly water retention and strong androgenic effects. These included gyno, accelerated hair growth, receding hair-lines, aggressiveness, higher blood pressure, acne, and increased fat deposits (due to aromatization). Since testosterones are metabolized by the liver fairly easily, alarming elevated liver enzymes occurred in very high dosages only… usually.
Anabolic Steroid Guide reference
Testosterone enantate is an ester of the naturally occurring androgen, testosterone. It is responsible for the normal development of the male sex characteristics. In the event of insufficient testosterone production an almost complete balance of the functional, anatomic, and psychic deficiency symptoms can be achieved by substituting testosterone." (Excerpt from the package insert of the German pharmaceutical group, Jenapharm GmbH for its compound Testosteron-Depot.)
These lines clearly describe what an important and effective hormone testosterone is. One of the many testosterone substances is the testosterone enanthate. In a man it is normally used to treat hypogonadism resulting from androgen deficiency (1) and anemia (2). Surprisingly, in medical schools testosterone enanthate is also used in women and children. Boys and male youth take it as growth therapy and women take it as an "additive treatment for certain growth forms of the nipples during post-menopause". In bodybuilding, however, it is THE "mass building steroid." No matter what you think of Dianabol, Parabolan, Anadrol 50, FinaJect, and others, when it comes to strength, muscle mass, and rapid weight gains, testosterone is still the "King of the Road." Testosterone enanthate is the European counterpart to Testosterone cypionate which is predominantly available in the U.S. (see also Test. Cyp.). Testosterone enanthate, as most trade names already suggest, is a long-acting depot steroid. Depending on the metabolism and the body's initial hormone level it has a duration of effect of two to three weeks so that theoretically very long intervals between injections are possible. Although Testosterone enanthate is effective for several weeks, it is injected at least once a week in body-building, powerlifting, and weightlifting. This, by all means, makes sense since Testosterone enanthate has a plasma half-life time in the blood of only one week.
The decisive advantage of Testosterone enanthate, however, is that this substance has a very strong androgenic effect and is coupled with an intense anabolic component. This allows almost everyone, within a short time, to build up a lot of strength and mass. The, rapid and strong weight gain is combined with distinct water retention since a retention of electrolytes and water occurs. A pleasant effect is that the enormous strength gain goes hand in hand with the water retention. Weightlifters and powerlifters, especially in the higher weight classes, appreciate this characteristic. In this group, Testosterone enanthate, Testosterone cypionate, and Sustanon (see also Sustanon) are the number one steroids; this is also clearly reflected in the dosages. Dosages of 500 mg, 1000 mg or even 2000 mg per day are no rarity-mind you, per day, not per week. Sports disciplines requiring a high degree of raw power, aggressiveness, and stamina offer an excellent application for Depot-Testosterone. The distinct water retention has also other advantages. Those who have problems with their joints, shoulder cartilages or whose intervertebral disks, due to years of heavy training, show the first signs of wear, can get temporary relief by taking testosterone.
For the bodybuilder, the water retention that goes hand in hand with Testosterone enanthate cuts both ways. Certainly, one gets rapidly massive and strong; however, one's reflected image after a few weeks often shows completely flat, watery, and puffy muscles. The muscles appear as if they have been pumped up with air' to new dimensions, yet during flexing nothing happens. Those who do not believe this should bother to go visit the so-called "bodybuilding champions" during the OFF-season when these exaggerated quantities of "Testo" come in. A look at the now defunct bodybuilding magazine WBF makes it even clearer. An additional problem when taking Testosterone enanthate is that the conversion rate to estrogen is very high. This, on one hand, leads the body to store more fat; on the other hand, feminization symptoms (gynecomastia) are not unusual. However, it must be clearly stated that this depends on the athlete's predisposition. By all means, there are athletes who even with 1000 mg +/week do not show feminization symptoms or fat deposits and who suffer very low water retention. Others, however, develop pain in their nipples by simply looking at a Testoviron-Depot ampule. Yet the additional intake of Nolvadex and Proviron should be considered at a dosage level of 500 mg+ /week. As already mentioned, Testo is effective for everyone, whether a beginner or Mr. Olympia. Testosterone enanthate also strongly promotes the regeneration process. This leads to distinctly shorter overcompensation phases, an increased feeling of well-being, and a distinct energy increase. This is also the reason why several athletes are able to work out twice daily for several hours six times a week and continue to build up mass and strength. Those who can work out again two hours after a hard leg workout know that Testo works. Athletes who take Testosterone enanthate report an excessively strong pump effect during training. This "steroid pump" is attributed to an increased blood volume with a higher oxygen supply and a higher quantity of red blood cells. Those who take megadoses of Testosterone enanthate will already feel an enormous pump in their upper thighs and calves when climbing stairs. Despite this we recommend that steroid novices stay away from all testosterone compounds. To make it very clear: Those who have never taken steroids do not yet need any testosterone and should wait until later when the "weaker" steroids begin to have little effect. For the more advanced, Testosterone enanthate can either be taken alone or in combination with other compounds.
For adding mass Testosterone enanthate combines very well with Anadrol 50, Dianabol, Deca-Durabolin, and Parabolan. As an example, a stack of 100 mg Anadrol 50/day, 200 mg Deca-Durabolin/ week, and 500 mg Testosterone enanthate/week works well. After six weeks of intake the Anadrol 50, for example, could be replaced by 40 mg Dianabol/day. Principally, Testosterone enanthate can be combined with any steroid in order to gain mass. Apparently a synergetic effect between the androgen, Testosterone enanthate, and the anabolic steroids occurs which results in their bonding witli several receptors. Those who draw too much water with Testosterone enanthate and Dianabol or Anadrol, or who are more interested in strength without gaining 20 pounds of body weight should take Testosterone enanthate together with Oxandrolone or Winstrol. The generally taken dose as already mentioned varies from 250 mg/ week up to 2000 mg/day. In our opinion the most sensible dosage for most athletes is between 250-1000 mg/week. Normally a higher dosage should not be necessary. When taking up to 500 mg/week the dosage is normally taken all at once, thus 2 ml of solution are injected. A higher dosage should be divided into two injections per week. The quantity of the dose should be determined by the athlete's developmental stage, his goals, and the quantity of his previous steroid intake. The so called beach and disco bodybuilders do not need 1000 mg of Testosterone enanthate/week. Our experience is that the Testosterone enanthate dosage for many, above all, depends on their financial resources. Since it is not, by any means, the most economic testosterone, most athletes do not take too much. Others switch to the cheaper Omnadren and because of the low price continue "shooting" Omnadren.
Testosterone enanthate has a strong influence on the hypothalamohypophysial testicular axis. The hypophysis is inhibited by a positive feedback. This leads to a negative influence on the endogenic testosterone production. Possible effects are described by the German Jenapharm GmbH in their package insert for the compound Testosteron Depot: " In a high-dosed treatment with testosterone compounds an often reversible interruption or reduction of the spermatogenesis in the testes is to be expected and consequently also a reduction of the testes size." Consequently, after reading these statements, additional intake of HCG should be considered. Those who take Testosterone enanthate should consider the intake of HCG every 6-8 weeks. An injection of 5000 I.U. every fifth day over a period of 10 days (a total of 3 injections) helps to reduce this problem. At the end of the testosterone treatment the administration of HCG, Clomid, Nolvadex and Clenbuterol is now quite common. To some extent the use of these compounds helps absorb the catabolic phase and helps elevate the endogenic testosterone level. By this method the strength and mass loss which occur in any event can be reduced. Those who go off Testosterone enanthate after several weeks of use will wonder how rapidly their body weights and former voluminous muscles will decrease. Even a slow tapering-off phase, that is reducing the dosage step by step, will not prevent a notice-able reduction. The only options available to the athlete consist of taking testosterone-stimulating compounds (HCG, Clomid, Cyclofenil), anti-catabolic substances (Clenbuterol, Ephedrine), or the very expensive growth hormones, or of switching to milder steroids (Deca-Durabolin, Winstrol, Primobolan). Most can get massive and strong with Testosterone enanthate. However, only very few are able to retain their size after discontinuing the compound. This is also one of the reasons why really good bodybuilders, powerlifters, weightlighters, and others take the "stuff " all year long.
The side effects of Testosterone enanthate are mostly the distinct androgenic effect and the increased water retention. This is usually the reason for the frequent occurrence of hypertony (3). Those who have a predisposition for high blood pressure or whose blood pressure is elevated when they begin taking Testosterone enanthate should have it periodically checked by a physician. If necessary the intake of an antihypertensive drug (4) such as Catapresan is advisable. Many athletes experience a strong acne vulgaris with Testosterone enanthate which manifests itself on the back, chest, shoulders, and arms more than on the face. Athletes who take large quantities of Testo can often be easily recognized because of these characteristics. It is interesting to note that in some athletes these characteristics only occur after use of the compound has been discontinued, which implies a rebound effect. In severe cases the medicine Accutane can help. The already discussed feminization symptoms, especially gynecomastia, require the intake of an antiestrogen. Sexual overstimulation with frequent erections at the beginning of intake is normal. In young athletes, "in addition to virilization, testosterone can also lead to an accelerated growth and bone maturation, to a premature epiphysial closing of the growth plates and thus a lower height" (Jenapharm GmbH, package insert for Testosteron-Depot).' Since mostly taller athletes are successful in bodybuilding, young adults should reflect carefully before taking any anabolic/andro-genic steroids, in particular, testosterone.
Other possible side effects are testicular atrophy, reduced spermatogenesis, and especially an increased aggressiveness. Those who transfer this aggressiveness to their training and not their environment do not have to worry. Unfortunately this is not the case in some athletes who take Testosterone enanthate. Testosterone and Finaject are both primary reasons for some eruptions. In particular, high doses are in part responsible for anti-social behavior among its users. One can talk here of a sort of "superman syndrome" that occurs in some users. Although Testosterone enanthate is broken down through the liver, this compound is only slightly toxic when taken in a reasonable dose; therefore, changes of the liver values do not occur as often as with the oral I 7-alpha alkylated steroids. Further potential side effects can be deep voice and accelerated hair loss.
Women should normally avoid its intake since it could result in unpleasant androgen-linked side effects. The use of testosterone in women may cause symptoms of virilization such as acne vulgaris, hirsutism (5), androgenetic alopecia (6), voice changes, and occasional clitorial hypertrophy and an unnaturally perceived increase in libido. Changes in voice and alopecia must be classified as irreversible, hirsutism and clitorial hypertrophy as in part reversible." Women who are not afraid of this are found at many competition scenes. In our opinion, 250 mg is the maximum quantity of Testosterone enanthate that a female athlete should take each 7-10 days. However in competition bodybuilding and especially in powerlifting much higher dosages and shorter injection intervals have been observed in women.
Another interesting side effect of Testosterone enanthate is mentioned in the bodybuilding magazine Muscle Media 2000, June July 1993 on page 45. Judging whether this is positive or negative is left to the reader. 'A few years ago, the Lancet Medical Journal of England reported that they found testosterone (the prototype anabolic steroid) to be a remarkably effective form of male birth control. Researchers conducted a 12 month study which included 270 men and determined that weekly injections of the hormone testosterone were 'safe, stable, and effective.' They discovered that weekly testosterone injections had a success rate of 99.2% as a birth control method. That makes it more effective than the birth control pill (97%) and much more effective than condoms (88%). The study also revealed that the effects of the contraceptive injections were entirely reversible upon discontinuing administration of the drug and that the testosterone injections produced minimal side effects."
Similar studies with identical data are also in progress at a German university clinic. Although this is not part of the actual subject of this book, these results stress at least the need for testosterone stimulating compounds during and after the intake of Testosterone enanthate. Since it is effective for such a long period of time, Testosterone enanthate is always taken more frequently by athletes during their "steroid intervals." An injection of 250 mg every 2-3 weeks helps maintain strength and mass. Whether this application makes sense remains to be seen; the fact is that it works.
(1) Inadequate function of the genital glands (2) Anemia (3) High blood pressure (4) To reduce high blood pressure (5) Increased hair growth in face and on legs (6) Androgenic-linked loss of hair on the scalp
Newbies Research Guide reference
This drug is very similar to Depo-Testosterone; it is injectable testosterone in oil. It is high androgenic, high anabolic, aromatizes easily, and is moderately toxic to the liver. The main difference between Delatestryl and Depo-Testosterone is that Dela has a longer life. It remains active for over two weeks. This drug does tend to cause very bad edema in some, which results in that familiar puffy look. This is all right for a lot of powerlifters who actually gain strength from the excess water. The majority prefers dept, but some feel Dela is just as good or even better for gaining size and strength. The real advantage of Dela is that a shot of Dela is only required about every 10 days to keep it working well. This can save comfort and money for the user. Nolvadex should always be used along with this drug. Effective dosages range from 1cc to 3ccs every 10 days.
Wlliam Llewellyn (2011) - Anabolics
L. Rea (2002) - Chemical Muscle Enhancement Bodybuilders Desk Reference
Anabolic Steroid Guide
Newbies Research Guide