BPC-157 — body protection compound 157

BPC-157 is a peptide that occurs naturally in the human stomach. As a research compound, it has been shown to heal numerous body tissues including the skin, muscle, and bone, as well as ligament and tendon. Its underlying mechanism is not fully understood. However, it does appear to increase the density of growth hormone receptors in some tissues.

Bodybuilders and other athletes use BPC-157 to speed repair of damaged muscle and joint tissue. Some underground experts have touted it as 'the most powerful healing drug on earth for injuries', after experiencing that administration of this compound let injuries, which usually take 10-12 weeks to heal, healed within 2-3 weeks. Anecdotes suggest that BPC-157 is effective when administered immediately after an injury occurs, but also when taken in order to fix an improperly healed injury that occurred years ago. Although athletes inject this peptide, BPC-157 is stable in gastric juice and therefore orally available. Animal studies have proven topical administration of BPC-157 to be effective as well.

In dozens of animal studies, BPC-157 has been shown to stimulate repair processes of the mucosa. In animal studies, a synthesized yet identical version of this molecule accelerates the healing of ulcers and other gastric and duodenal lesions, protects the liver from toxic compounds, speeds up the healing of lung tissue after inhalation of aggressive gasses, protects the mucosa in the nose from capsaicin, and diminishes the side effects of chemotherapy with doxorubicine in the heart. In other animal studies BPC-157 accelerates the healing of wounds and broke bones and burn wounds, stimulates healing of transected nerves, enhances the healing of transected ligaments, rotator cuff tear injury, and Achilles tendons. In one animal study, BPC-157 even stimulated the reattachment of a severed Achilles tendon to the bone! Finally, BPC-157 enhances the healing of surgically transected or crushed muscle tissue.

BPC-157 reinforces healing processes by stimulating angiogenesis (production of blood vessels) in tissues, probably by activating the 'blood vessel hormone' VEGF.

Brand name BPC-157, Body protection compound 157

BPC-157 History

BPC-157 maked its first appearance in scientific literature in 1992, in an article by the Croatian scientist Predrag Sikiric and his coworkers. Most of the research into BPC-157 is done by Sikiric, and has been sponsored by the Croatian pharmaceutical company Pliva. Financial difficulties prompted Pliva in 2005 to halt the investments in BPC-157. Attempts of Merck, which had been a business partner of Pliva for years, to buy the BPC-157 patents and research, have failed. Even though its future as a drug remain unclear, a few years later web shops specializing in research chemicals began selling it.

How is BPC-157 supplied

BPC-157 is not available as a pharmaceutical product at this time. Standard dosage information is unavailable. As a research chemical, BP-157 is sold as a liquid, or as a powder that has to be dissolved in bacteriostatic water before administration. The most popular version is currently produced by Diagen in Slovenia. At room temperature, BPC-157 can be kept for a few months. In a refrigerator or freezer it can be kept for 6 months and 24 months, respectively.

BPC-157 Side effects

In the scientific literature and experiences of users no side effects of BPC-157 have surfaced yet. However, as this drug has not yet been approved as a pharmaceutical agent its safety, and its propensity for side effects may not be well understood at this time. We want to stress here that we know of only one human study on the effects of BPC-157. That study, which concerned test subjects with mild-to-moderate ulcerative colitis that were given BPC-157 rectally, wasn't published in peer-reviewed literature, but presented at a conference. All the other studies are in vitro or used animal models.

Structural Characteristics of BPC-157

BPC-157 is a peptide - an pentadecapeptide, to put it precisely. It consists of 15 amino acids (Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala Gly Leu Val).

BPC-157 Administration

This drug is not available as a pharmaceutical product. Prescribing guidelines are unavailable.

BPC-157 is injected with insulin needles. When used off label, most athletes administer dosages of 200-300 microgram/day to accelerate healing of injuries. They inject 200-300 micrograms subcutaneous or intramuscular (not into the joints) as close as possible to the place where the injury occurred, one, two and sometimes even three times a day. Cycles last for 2-4 weeks, after which most underground sources advise an off-period of 2 weeks. If the injury needs further treatment, another cycle can be started.

BPC-157 Availability

No commercial preparations containing BPC-157 are known to exist. This drug is available on the black market in underground manufactured products only.

References

Wlliam Llewellyn (2017) - Anabolics

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